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Annotation 4860325006604

#158 #Cours #Dermatologie #Facultaires #IST #Médecine

Traitement de la syphilis du sujet séropositif pour le VIH Le traitement standard par la pénicilline est le même en cas de syphilis primaire ou secondaire du sujet séropositif pour le VIH. Une étude du LCR préalablement au traitement n'est pas justifiée sauf en cas de manifes- tations neurologiques ou ophtalmiques patentes (comme chez le patient séronégatif pour le VIH), ce qui nécessiterait un traitement par pénicilline G IV : 20 millions d'unités par jour pendant 10 à 15 jours. Les cyclines ne sont pas validées chez le patient séropositif pour le VIH. Chez les patients VIH engagés dans des pratiques à risque, on recommande la pratique d'une sérologie de syphilis au moins une fois par an.

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Annotation 4895909219596

#158 #Cours #Facultaires #IST #Maladies-infectieuses-et-tropicales #Médecine

Syphilis primaire : chancre (PUE6-158-2)

Témoigne de la réplication du tréponème au niveau de la porte d’entrée
Débute en moyenne 3 semaines après le contage
Ulcération classiquement indolore et à fond induré et propre, pouvant siéger sur les organes génitaux (peau ou muqueuse, y compris col de l’utérus), la muqueuse anale voire la muqueuse buccale
Associé à une ou plusieurs adénopathie(s), le plus souvent inguinale(s) (selon le siège du chancre), non inflammatoire(s).
Le chancre et l’adénopathie disparaissent spontanément.

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Flashcard 5038904315148

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis #has-images

Question

Roséole syphilitique

Elle passe souvent inaperçue car peu intense et transitoire (elle disparaît spontanément en [...] à [...] jours).

[unknown IMAGE 4860288830732]

Answer

Roséole syphilitique

Disparaît en 7 à 10 jours

Absence de signes fonctionnels

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première éruption de la syphilis secondaire survenant dans les 6 semaines qui suivent le chancre. Elle passe souvent inaperçue car peu intense et transitoire (elle disparaît spontanément en 7 à <span>10 jours). Elle se caractérise par : • des macules rose pâle (figure 158.3) de 5 à 15 mm de diamètre, disséminées sur le tronc ; • une absence de signes fonctionnels à ce stade </sp

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Flashcard 5042851155212

Tags

#158 #Cours #Facultaires #IST #Maladies-infectieuses-et-tropicales #Médecine

Question

Les partenaires sexuels sont systématiquement dépistés, puis traités :

Syphilis :
- Traitement d’emblée si le dernier rapport sexuel date de moins de [...] semaines
- Traitement selon les résultats de la sérologie s’il date de plus de [...] semaines

Answer

6 semaines

Si Syphilis incertaine chez le partenaire et moins de 6 semaines : sérologie, à répéter à M+3 si négative

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dépistés, puis traités : Infection à gonocoque et Chlamydia : traitement d’emblée du/des partenaire(s) régulier(s). Syphilis : Traitement d’emblée si le dernier rapport sexuel date de moins de <span>6 semaines Traitement selon les résultats de la sérologie s’il date de plus de 6 semaines. Infection à HPV : pas de dépistage en dehors du frottis cervical et/ou de l'examen prodologique

Annotation 6453149699340

Incremental reading is a software-assisted method for learning and retaining information from reading, which involves the creation of flashcards out of electronic articles. "Incremental reading" means "reading in portions". Instead of a linear reading of articles one at a time, the method works by keeping a large reading list of electronic articles or books (often dozens or hundreds of them) and reading parts of several articles in each session. Articles in the reading list are prioritized by the user. In the course of reading, key points of articles are broken up into flashcards, which are then learned and reviewed over an extended period of time with the help of a spaced repetition algorithm.

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Incremental Reading
Incremental reading is a software-assisted method for learning and retaining information from reading, which involves the creation of flashcards out of electronic articles. "Incremental reading" means "reading in portions". Instead of a linear reading of articles one at a time, the method works by keeping a large reading list of electronic articles or books (often dozens or hundreds of them) and reading parts of several articles in each session. Articles in the reading list are prioritized by the user. In the course of reading, key points of articles are broken up into flashcards, which are then learned and reviewed over an extended period of time with the help of a spaced repetition algorithm. This use of flashcards at later stages of the process is based on the spacing effect (the phenomenon whereby learning is greater when studying is spread out over time) and the testing e

Annotation 7095940680972

Méningite Syphilitique

#Acute #Aigue #Clinical #Clinique #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis

Patients with syphilitic meningitis usually present in a manner similar to that of patients with other forms of aseptic meningitis—that is, with complaints of headache, nausea, and vomiting. In one series, these complaints were present in 91% of patients. 237 Meningismus occurred in 59% and fever in less than half of the patients with syphilitic meningitis. Seizures occurred in 17% of patients, whereas cranial nerve palsies were found in 45% of cases (most commonly cranial nerves VII and VIII, followed by II, III, VI, and V).

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Annotation 7095945399564

Meningovascular syphilitis

#Acute #Aigue #Clinical #Clinique #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Most patients experience weeks to months of episodic prodromal symptoms and signs, including headache or vertiginous episodes, personality changes (e.g., apathy or inattention), behavioral changes (e.g., irritability or memory impairment), insomnia, or seizures. Focal deficits, which reflect episodes of ischemia in regions of the brain with involved blood vessels (usually in the distribu- tion of the middle cerebral artery), may also occur; if untreated, these deficits may progress to a stroke syndrome with attendant irreversible neurologic deficits

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Annotation 7598437960972

Sturm–Liouville Problem

In mathematics and its applications, a Sturm-Liouville problem is a second-order linear ordinary differential equation of the form:$\frac{\mathrm{d}}{\mathrm{d} x}\left[p(x) \frac{\mathrm{d} y}{\mathrm{~d} x}\right]+q(x) y=-\lambda w(x) y$ for given functions $p(x), q(x)$ and $w(x)$, together with some boundary conditions at extreme values of $x$.

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Annotation 7598441368844

Defintion of the symmetric/self-adjoint operator of S-L system

For the S-L system $\frac{\mathrm{d}}{\mathrm{d} x}\left[p(x) \frac{\mathrm{d} y}{\mathrm{~d} x}\right]+q(x) y=-\lambda w(x) y$, we can define a symmetric/self-adjoint operator of S-L system: $\mathscr{L}=\frac{-1}{r}\left[\frac{\mathrm{d}}{\mathrm{d} x}\left(p(x) \frac{\mathrm{d}}{\mathrm{~d} x}\right)+q(x)\right]$ and transform the original equation to $\mathscr{L}y=\lambda y$

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Flashcard 7600869346572

Tags

#158 #Cours #Dermatologie #Facultaires #IST #Médecine

Question

Chez les patients VIH engagés dans des pratiques à risque, on recommande la pratique d'une sérologie de syphilis au moins [fréquence?].

Answer

Une fois par an

Collège de dermatologie

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cyclines ne sont pas validées chez le patient séropositif pour le VIH. Chez les patients VIH engagés dans des pratiques à risque, on recommande la pratique d'une sérologie de syphilis au moins <span>une fois par an. <span>

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Flashcard 7600871705868

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Syphilis secondaire :

Témoigne de la dissémination hématogène du tréponème
Débute en général [...] semaines après le chancre, mais peut être observée jusqu’à [...] après la contamination

Answer

SYPHILIS SECONDAIRE

Débute en général à 6 semaines après le chancre

Observée jusqu’à 1 an après la contamination

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Syphilis secondaire : Témoigne de la dissémination hématogène du tréponème Débute en général 6 semaines après le chancre, mais peut être observée jusqu’à 1 an après la contamination Les manifestations cutanées et muqueuses sont les plus fréquentes : Précocement : Roséole (éruptio

Flashcard 7600874851596

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Où débute et prédomine la roséole syphilitique ?

Answer

Roséole : éruption maculeuse rose pâle débutant et prédominant au TRONC

Syphilis SECONDAIRE

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nème Débute en général 6 semaines après le chancre, mais peut être observée jusqu’à 1 an après la contamination Les manifestations cutanées et muqueuses sont les plus fréquentes : Précocement : <span>Roséole (éruption maculeuse rose pâle débutant et prédominant au tronc, disparaissant en 1 à 2 mois) Plus tardive : Syphilides (papules sombres squameuses classiquement palmo-plantaires mais pouvant toucher tous les téguments, contagieuses si elles sont ulcérées, guérissant en quelques

Flashcard 7600877997324

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

En combien de temps disparait la roséole syphilitique ?

Answer

Roséole : disparaissant en 1 à 2 MOIS

Syphilis SECONDAIRE

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Flashcard 7600883764492

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Quelles sont les manifestations cutanées précoces de la syphilis secondaire ? tardives ?

Answer

SYPHILIS SECONDAIRE

Les manifestations cutanées et muqueuses sont les plus fréquentes :

Précocement :
- Roséole
Plus tardive :
- Syphilides
- Plaques muqueuses

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span> Syphilis secondaire : Témoigne de la dissémination hématogène du tréponème Débute en général 6 semaines après le chancre, mais peut être observée jusqu’à 1 an après la contamination Les manifestations cutanées et muqueuses sont les plus fréquentes : Précocement : Roséole (éruption maculeuse rose pâle débutant et prédominant au tronc, disparaissant en 1 à 2 mois) Plus tardive : Syphilides (papules sombres squameuses classiquement palmo-plantaires mais pouvant toucher tous les téguments, contagieuses si elles sont ulcérées, guérissant en quelques mois, PUE6-158-3) Plaques muqueuses (lésions en relief, plus ou moins érosives, de la bouche, des organes génitaux, conta-gieuses) L’alopécie est rare Uvéite, rétinite (présentations ophtalmiques fréquentes) Polyadénopathie superficielle Tous les autres organes peuvent être touchés (arthrite, hépatite...) : la syph

Flashcard 7600886123788

Tags

#Maladies-infectieuses-et-tropicales #Syphilis

Question

Syphilis secondaire :

L’alopécie est [fréquence ?]

Answer

RARE

SYPHILIS SECONDAIRE

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si elles sont ulcérées, guérissant en quelques mois, PUE6-158-3) Plaques muqueuses (lésions en relief, plus ou moins érosives, de la bouche, des organes génitaux, conta-gieuses) L’alopécie est <span>rare Uvéite, rétinite (présentations ophtalmiques fréquentes) Polyadénopathie superficielle Tous les autres organes peuvent être touchés (arthrite, hépatite...) : la syphilis a été qualifiée

Flashcard 7600888745228

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis #Traitement

Question

La réaction d'Herxheimer qui est secondaire à la lyse des tréponèmes est [gravité?] dans la syphilis primaire

Answer

SANS GRAVITÉ

Dans la Syphilis PRIMAIRE

Faible charge en tréponèmes ?

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jections intramuscu- laires : une injection intramusculaire unique de 2,4 millions d'unités de benzathine pénicilline G. La réaction d'Herxheimer qui est secondaire à la lyse des tréponèmes est <span>sans gravité dans la syphilis primaire <span>

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Flashcard 7600891628812

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Syphilis primaire

Le chancre syphilitique d’inoculation apparaît [...] après le contage.

Answer

Trois semaines

Syphilis PRIMAIRE

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Syphilis primaire Le chancre syphilitique d’inoculation apparaît trois semaines après le contage : c’est une érosion indolore, localisée surtout à la lèvre ou à la langue, propre et bien limitée, à bord régulier avec, quelquefois, un halo érythémateux. Le fond est

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Flashcard 7600893988108

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Syphilis primaire

CMF
Le chancre syphilitique d’inoculation : c’est une érosion [douleur ?], localisée surtout à [...] ou à [...] , propre et [aspect?] limitée, à bord [...] avec, quelquefois, un [peau péri-lésionnelle ?]

Answer

INDOLORE
Localisée surtout à la LÈVRE ou à la LANGUE
PROPRE et BIEN limitée
Bord RÉGULIER avec, quelquefois, un HALO ERYTHÉMATEUX.

Syphilis PRIMAIRE

Attention, parfois multiples chancres (gorge, anus, verge, vagin, col utérus, ...)

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Flashcard 7600896347404

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

À quel stade se rencontre la perlèche syphilitique ?

Answer

Syphilis secondaire TARDIVE

Symptôme cutané rarement isolé

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, fissuraire, voire macéré. • La lésion peut s'étendre à la peau adjacente et au reste de la lèvre (chéilite). • Diagnostic différentiel : perlèche streptococcique (parfois associée à Candida), <span>syphilitique (symptôme cutané rarement isolé, syphilis secondaire tardive), herpétique (vésicule, évo- lution par poussée rémission, symptômes sensitifs associés), carentielle (carence martiale, carence en zinc ; terrain évocateur) <span>

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Flashcard 7600899230988

Tags

#Clinique #Glomerulopathies #Maladies-infectieuses-et-tropicales #Nephrologie #Syphilis

Question

Citer 6 causes infectieuses de GEM

Answer

Causes de Glomérulopathie Extra-Membraneuse :

Hépatite B
Hépatite C
Syphilis
Lèpre
Filariose
Plasmodium malariae

Causes classiques mais rares ++

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s Surtout si âge > 50 ans • Cancers pulmonaires, mammaires, coliques, mélanomes Lupus érythémateux disséminé Femme de 20 à 55 ans Autres maladies auto-immunes Sjögren, thyroïdite… Infections <span>Causes classiques mais rares ++ [hépatite B (et C), syphilis, lèpre, filariose, Plasmodium malariae] Médicaments AINS <span>

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Flashcard 7600902638860

Tags

#Acute #Aigue #Clinical #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Qu'est-ce qui différencie cliniquement la méningite syphilitique et l'attente méningo-vasculaire de la syphilis ? (2)

Answer

Tempo
Déficits neurologiques focaux

"Meningovascular syphilis is clinically distinguished from syphilitic meningitis temporally and on the basis of focal neurologic findings as a result of focal syphilitic arteritis, which almost always occurs in association with meningeal inflammation"

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Meningovascular syphilis is clinically distinguished from syphilitic meningitis temporally and on the basis of focal neurologic findings as a result of focal syphilitic arteritis, which almost always occurs in association with meningeal inflammation. 166

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Flashcard 7600905260300

Tags

#Acute #Aigue #Clinical #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Quels sont les symptômes prodromaux de la l'atteinte méningo-vasculaire de la Syphilis ? (6)

Answer

Céphalée
Vertiges
Troubles de la personnalité
Troubles du comportement
Insomnie
Épilepsie

"Most patients experience WEEKS to MONTHS of episodic prodromal symptoms and signs, including headache or vertiginous episodes, personality changes (e.g., apathy or inattention), behavioral changes (e.g., irritability or memory impairment), insomnia, or seizures."

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Most patients experience weeks to months of episodic prodromal symptoms and signs, including headache or vertiginous episodes, personality changes (e.g., apathy or inattention), behavioral changes (e.g., irritability or memory impairment), insomnia, or seizures. Focal deficits, which reflect episodes of ischemia in regions of the brain with involved blood vessels (usually in the distribu- tion of the middle cerebral artery), may also occur; if

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Flashcard 7600908668172

Tags

#Acute #Aigue #Clinical #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Quelle est la proportion de partient avec une méningite syphilitique qui se présente avec CÉPHALÉE +/- NAUSÉE +/- VOMISSEMENTS ?

Answer

91 %

"Patients with syphilitic meningitis usually present in a manner similar to that of patients with other forms of aseptic meningitis—that is, with complaints of headache, nausea, and vomiting.
In one series, these complaints were present in 91% of patients."

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Patients with syphilitic meningitis usually present in a manner similar to that of patients with other forms of aseptic meningitis—that is, with complaints of headache, nausea, and vomiting. In one series, these complaints were present in 91% of patients. 237 Meningismus occurred in 59% and fever in less than half of the patients with syphilitic meningitis. Seizures occurred in 17% of patients, whereas cranial nerve palsies were found in

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Flashcard 7600911813900

Tags

#Acute #Aigue #Clinical #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Méningite Syphilitique

Meningismus occurred in [...]% and fever in less than [porportion?] of the patients with syphilitic meningitis.

Answer

Meningismus 59 %
Fever in less than half

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s with other forms of aseptic meningitis—that is, with complaints of headache, nausea, and vomiting. In one series, these complaints were present in 91% of patients. 237 Meningismus occurred in <span>59% and fever in less than half of the patients with syphilitic meningitis. Seizures occurred in 17% of patients, whereas cranial nerve palsies were found in 45% of cases (most commonly cr

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Flashcard 7600914173196

Tags

#Acute #Aigue #Clinical #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Méningite Syphilitique

Seizures occurred in [...]% of patients, whereas cranial nerve palsies were found in [...] % of cases.

Answer

Méningite Syphilitique

Seizures : 17 %

Cranial nerve palsie : 45 %

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ng. In one series, these complaints were present in 91% of patients. 237 Meningismus occurred in 59% and fever in less than half of the patients with syphilitic meningitis. Seizures occurred in <span>17% of patients, whereas cranial nerve palsies were found in 45% of cases (most commonly cranial nerves VII and VIII, followed by II, III, VI, and V). <span>

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Flashcard 7600916532492

Tags

#Acute #Aigue #Clinical #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Quels sont les nerfs crâniens les plus souvents atteintes au cours de la méningite syphilitique ?

Answer

Méningite Syphilitique

Facial (VII)
Cochléo-vestibulaire (VIII)

"Most commonly cranial nerves VII and VIII, followed by II, III, VI, and V"

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eningismus occurred in 59% and fever in less than half of the patients with syphilitic meningitis. Seizures occurred in 17% of patients, whereas cranial nerve palsies were found in 45% of cases <span>(most commonly cranial nerves VII and VIII, followed by II, III, VI, and V). <span>

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Flashcard 7600920726796

Tags

#Acute #Aigue #Clinique #HIV #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #VIH

Question

In one report, [...]% of patients with HIV with early syphilis undergoing lumbar puncture had evidence of CNS infection.

Answer

90 %

"In one report, 90 % of patients with HIV with early syphilis undergoing lumbar puncture had evidence of CNS infection."

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In one report, 90% of patients with HIV with early syphilis undergoing lumbar puncture had evidence of CNS infection. 168

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Flashcard 7600924658956

Tags

#Acute #Aigue #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Gummas are late manifestations of [stade?] syphilis and may occur anywhere; gummatous neurosyphilis is rare.

Answer

Tertiary

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Gummas are late manifestations of tertiary syphilis and may occur anywhere; gummatous neurosyphilis is rare.

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Flashcard 7600927804684

Tags

#Acute #Aigue #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Méningite Syphilitique

The incidence of syphilitic meningitis is greatest in the first [...] years after infection

Answer

2 years

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The incidence of syphilitic meningitis is greatest in the first 2 years after infection and is estimated to occur in only 0.3% to 2.4% of untreated syphilis cases. In contrast, meningovascular syphilis is found in 10% to 12% of individuals with CNS in

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Flashcard 7600930163980

Tags

#Acute #Aigue #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Quelle est l'incidence de la méningite syphilitique parmi les patients atteints de Syphilis et non traités ?

Answer

De 0,3 à 2,4 %

"The incidence of syphilitic meningitis is greatest in the first 2 years after infection and is estimated to occur in only 0.3% to 2.4% of untreated syphilis cases"

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Flashcard 7600932523276

Tags

#Acute #Aigue #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Meningovascular syphilis occurs months to years after syphilis acquisition (peak incidence, approximately [...] years).

Answer

7 years

Meningovascular ≠ Meningitis

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cases. In contrast, meningovascular syphilis is found in 10% to 12% of individuals with CNS involvement 169 and occurs months to years after syphilis acquisition (peak incidence, approximately <span>7 years). <span>

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Flashcard 7600935406860

Tags

#Acute #Aigue #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Quelle est la proportion de patients avec une atteinte syphilitique du SNC qui développent une syphilis méningovasculaire ?

Answer

10 à 12 %

"Meningovascular syphilis is found in 10% to 12% of individuals with CNS involvement"

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Flashcard 7600939863308

Tags

#Acute #Aigue #Clinique #Maladies-infectieuses-et-tropicales #Meningite #Meningitis #Meningo-encephalite #Meningoencephalitis #Syphilis

Question

Quelles sont les 4 formes cliniques / syndromes neurologiques de la Syphilis ?

Answer

Méningite
Méningovasculaire
Parenchymateuse
Gommes

"Clinical neurosyphilis can be divided into four distinct syndromes : syphilitic meningitis, meningovascular syphilis, parenchymatous neurosyphilis, and gummatous neurosyphilis. Some overlap may be seen in the clinical and laboratory findings of these syndromes."

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Clinical neurosyphilis can be divided into four distinct syndromes 166–168 : syphilitic meningitis, meningovascular syphilis, parenchymatous neurosyphilis, and gummatous neurosyphilis. Some overlap may be seen in the clinical and laboratory findings of these syndromes.

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Annotation 7600940911884

The "Reduce of Order" Method for non-constant-coefficients 2nd order linear homogeneous ODE

About most of non-constant coefficients 2nd linear homogeneous ODE

$a_{2}(x)\frac{d^{2}y}{dx^{2}}+a_{1}(x)\frac{dy}{dx}+a_{0}(x)y(x)=0$

there is NO universal recipe. In general, it can only tried & error.
However, if we find 1 solution, there exist a recipe to find the 2nd:
1. Assume we have 1 solution: $y_{1}(x)$. Propose ansatz: $y_{2}(x)=V(x)y_{1}(x)$, with some unknow function $V(x)$.
2. Derivative $y''$, $y'$ terms, plug them to the original ODE.
3. Let $\displaystyle w= \frac{dV}{dx}$ and reduce it to the first order equation.$a_{2}y_{1} \frac{dw}{dx}+(2a_{2}y_{1}'+a_{1}y_{1})w=0$
4. Solve it and then we can get $\displaystyle V(x)=\int e^{-\int(2y_{1}'/y_{1}+a_{1}/a_{2})dx}dx+C$ and the general solution $\displaystyle y_{general}(x)=Ay_{2}(x)+By_{1}(x)=\left(A\int e^{-\int(2y_{1}'/y_{1}+a_{1}/a_{2})dx}dx+B+C\right)y_{1}(x)$

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Flashcard 7600944581900

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Quelle est classiquement la taille du chancre syphilitique ?

Answer

5 à 15 mm de diamètre

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(Syphilis) L'ulcération est unique, superficielle, non douloureuse, de 5 à 15 mm de diamètre, à fond propre, limite nette et base indurée. Les adénopathies inguinales sont fermes, indolores et souvent bilatérales

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Flashcard 7600946941196

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Quelles sont les caractéristiques cliniques des adénopathies satellites d'un chancre syphilitique ? (3)

Answer

Les adénopathies inguinales sont FERMES, INDOLORES et souvent BILATÉRALES

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Flashcard 7600949824780

Tags

#Diagnostic #Maladies-infectieuses-et-tropicales #Syphilis

Question

Quel est le délai entre l'apparition du chancre et la positivation de la sérologie syphilitique ?

Answer

Positivité en général 10 JOURS après le chancre (test tréponémique TPHA PUIS VDRL)

Délai d'incubation (donc avant le chancre) de la Syphilis de 3 à 4 semaines ( 10 - 90 jours )

Se méfier d'une sérologie TPHA pos VDRL neg : trop précoce ou tertiaire ?

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recommandé que le dépistage initial soit fait par un test tréponémique automatisé (EIA, ELISA) qualitatif, confirmé en cas de positivité par un test non tréponémique (VDRL ou RPR) quantitatif. <span>Positivité en général 10 jours après le chancre (test tréponémique puis VDRL). Tests tréponémiques (EIA, ELISA) : Témoigne de l’infection par le tréponème, mais non de l’activité de cette infection. Très spécifique, mais sans intérêt pour le suivi (reste positif

Flashcard 7600954019084

Tags

#Maladies-infectieuses-et-tropicales #Syphilis #Traitement

Question

Conduite à tenir si rapport sexuel avec une personne ayant la Syphilis ? (3 cas de figure)

Answer

En cas de contact sexuel avec une personne ayant la syphilis :

La syphilis est certaine chez le sujet source, examiner le patient contact :

Si contact PLUS DE 6 semaines, faire sérologie de la syphilis :
- Si POSITIVE : TRAITEMENT
- Si négative : refaire SÉROLOGIE à 3 mois

Si contact MOINS DE 6 semaines : TRAITER SYSTÉMATIQUEMENT le patient contact (une injection de benzathine pénicilline). Une sérologie de la syphilis sera bien sûr prélevée

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Sujets contacts sexuels En cas de contact sexuel avec une personne ayant la syphilis : • la syphilis est certaine chez le sujet source, examiner le patient contact : – si contact > 6 semaines, faire sérologie de la syphilis : – si + : traiter ; – si - : refaire à 3 mois ; – si contact < 6 semaines : traiter systématiquement le patient contact (une injection de benzathine pénicilline) - une sérologie de la syphilis sera bien sûr prélevée

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Flashcard 7600958737676

Tags

#Diagnostic #Maladies-infectieuses-et-tropicales #Syphilis

Question

En combien de temps le VDRL atteint son maximum au cours de la Syphilis primaire ?

Answer

Le VDRL grimpe progressivement pour atteindre son maximum vers le TROISIÈME à SIXIÈME mois de la maladie.

"Tous les profils sont observables au cours de la syphilis primaire (TPHA-/VDRL- ; TPHA +/VDRL- ; TPHA-/VDRL + ; TPHA +/VDRL +)"

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ifférents stades de la syphilis Au cours de la syphilis primaire : le TPHA et le VDRL sont négatifs dans les sept premiers jours du chancre. Passé ce délai, le TPHA est rapidement positif et le <span>VDRL grimpe progres- sivement pour atteindre son maximum vers le 3 e –6 e mois de la maladie. Tous les profils sont observables au cours de la syphilis primaire (TPHA-/VDRL- ; TPHA +/VDRL- ; TPHA-/VDRL + ; TPHA +/VDRL +). Au cours de la syphilis secondaire : les deux tests (TPHA et VDRL) sont toujours positifs <span>

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Flashcard 7600962145548

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Quelle est la prévalence des syphilides palmoplantaires au cours de la Syphilis secondaire ?

Answer

30 %

Inconstantes (environ 30 % des cas de syphilis secondaire) et souvent discrètes

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Syphilides palmoplantaires Elles sont très évocatrices car elles siègent électivement à cheval sur les plis palmaires (figure 158.5). Inconstantes (environ 30 % des cas de syphilis secondaire) et souvent discrètes mais évoca- trices de syphilis

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Flashcard 7600965029132

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Où siègent généralement les syphilides palmo-plantaires ?

Answer

Elles siègent électivement à cheval sur les plis palmaires

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Flashcard 7600971320588

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

[VoF] - La roséole syphilitique ne survient qu'une fois au cours de la Syphilis secondaire

Answer

FAUX

La Syphilis secondaire est marquée par plusieurs éruptions cutanéo-muqueuses entrecoupées de phases asymptomatiques de quelques semaines ou mois

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Syphilis secondaire Sa durée est en règle inférieure à un an. Elle est liée à la diffusion systémique du tréponème. Elle est marquée par plusieurs éruptions cutanéo-muqueuses entrecoupées de phases asymp- tomatiques de quelques semaines ou mois

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Flashcard 7600975777036

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

Environ [...] % des patients ayant présenté un chancre syphilitique vont présenter des signes de syphilis secondaire

Answer

30 % des chancres vont présenter des signes de secondaire

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régression spontanée du chancre sans séquelle en quelques semaines. Si le patient n'est pas traité, il sera apparemment guéri mais son état peut évoluer vers les stades plus tardifs : • environ <span>30 % des patients ayant présenté un chancre syphilitique vont présenter des signes de syphilis secondaire ; • des patients non traités peuvent également évoluer vers les stades de syphilis

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Flashcard 7600980233484

Question

About most of non-constant coefficients 2nd linear homogeneous ODE

$a_{2}(x)\frac{d^{2}y}{dx^{2}}+a_{1}(x)\frac{dy}{dx}+a_{0}(x)y(x)=0$

there is NO universal recipe. In general, it can only tried & error.
However, if we find 1 solution, there exist a recipe to find the 2nd: ["Reduce of Order" Method Steps]

Answer

1. Assume we have 1 solution: $y_{1}(x)$. Propose ansatz: $y_{2}(x)=V(x)y_{1}(x)$, with some unknow function $V(x)$.
2. Derivative $y''$, $y'$ terms, plug them to the original ODE.
3. Let $\displaystyle w= \frac{dV}{dx}$ and reduce it to the first order equation.$a_{2}y_{1} \frac{dw}{dx}+(2a_{2}y_{1}'+a_{1}y_{1})w=0$
4. Solve it and then we can get $\displaystyle V(x)=\int e^{-\int(2y_{1}'/y_{1}+a_{1}/a_{2})dx}dx+C$ and the general solution $\displaystyle y_{general}(x)=Ay_{2}(x)+By_{1}(x)=\left(A\int e^{-\int(2y_{1}'/y_{1}+a_{1}/a_{2})dx}dx+B+C\right)y_{1}(x)$

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The "Reduce of Order" Method for non-constant-coefficients 2nd order linear homogeneous ODE
}y}{dx^{2}}+a_{1}(x)\frac{dy}{dx}+a_{0}(x)y(x)=0\) there is NO universal recipe. In general, it can only tried & error. However, if we find 1 solution, there exist a recipe to find the 2nd: <span>1. Assume we have 1 solution: $y_{1}(x)$. Propose ansatz: $y_{2}(x)=V(x)y_{1}(x)$, with some unknow function $V(x)$. 2. Derivative $y''$, $y'$ terms, plug them to the original ODE. 3. Let $\displaystyle w= \frac{dV}{dx}$ and reduce it to the first order equation.$$$a_{2}y_{1} \frac{dw}{dx}+(2a_{2}y_{1}'+a_{1}y_{1})w=0$$$ 4. Solve it and then we can get $\displaystyle V(x)=\int e^{-\int(2y_{1}'/y_{1}+a_{1}/a_{2})dx}dx+C$ and the general solution $\displaystyle y_{general}(x)=Ay_{2}(x)+By_{1}(x)=\left(A\int e^{-\int(2y_{1}'/y_{1}+a_{1}/a_{2})dx}dx+B+C\right)y_{1}(x)$ <span>

Flashcard 7600982592780

Tags

#Clinique #Maladies-infectieuses-et-tropicales #Syphilis

Question

[VoF] - Le chancre Syphilitique laisse des séquelles

Answer

FAUX

Régression spontanée du chancre sans séquelle en quelques semaines.

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Évolution L'évolution se fait vers la régression spontanée du chancre sans séquelle en quelques semaines. Si le patient n'est pas traité, il sera apparemment guéri mais son état peut évoluer vers les stades plus tardifs : • environ 30 % des patients ayant présenté un chancre syphilitique vo

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Flashcard 7600986787084

Tags

#Aortite #Clinique #Maladies-infectieuses-et-tropicales #Syphilis #TopoAortite

Question

Syphilis primarily involves the [...] aorta.

Answer

THORACIC aorta

(50% ascending aorta, 20% arch, 30% descending aorta)

Riche en lymphatiques

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strains may have characteristic sites of infection. For example, Salmonella infects the abdominal aorta in 83% of cases and the thoracic aorta in 17% of cases. Syphilis primar- ily involves the <span>thoracic aorta (50% ascending aorta, 20% arch, 30% descending aorta), while tuberculosis involves the abdom- inal aorta in 2/3 of cases and the thoracic aorta in the remaining 1/3 of patients. 3

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Annotation 7600989932812

Definition of Laplace Transform

对一个函数$f(t)$做拉普拉斯变换，可以将其从实数域（$t$）转换到复数域（$s$），它的定义为

$\displaystyle {\mathcal {L}}[f(t)]=F(s)=\int _{0}^{\infty }f(t)e^{-st}\,\mathrm {d} t$

其中，$s=\sigma +i\omega$，$\sigma$和$\omega$为实数
- 积分下限从0开始，从控制工程的角度来讲，不需要去研究时间0点之前的事情，而是把这部分留给哲学家

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Flashcard 7601004875020

Question

对一个函数$f(t)$做拉普拉斯变换，可以将其从实数域（$t$）转换到复数域（$s$），它的定义为[...]

Answer

$\displaystyle {\mathcal {L}}[f(t)]=F(s)=\int _{0}^{\infty }f(t)e^{-st}\,\mathrm {d} t$

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Definition of Laplace Transform
对一个函数$f(t)$做拉普拉斯变换，可以将其从实数域（$t$）转换到复数域（$s$），它的定义为 $\displaystyle {\mathcal {L}}[f(t)]=F(s)=\int _{0}^{\infty }f(t)e^{-st}\,\mathrm {d} t$ 其中，$s=\sigma +i\omega$，$\sigma$和$\omega$为实数 - 积分下限从0开始，从控制工程的角度来讲，不需要去研究时间0点之前的事情，而是把这部分留给哲学家

Annotation 7601031089420

Laplace Transform of Common functions

#has-images

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Flashcard 7601039740172

Tags

#has-images

Question

Laplace Transform of Common functions

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Flashcard 7601046293772

Tags

#has-images

Question

Laplace Transform of Common functions

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Annotation 7601052847372

Incremental reading is a software-assisted method for learning and retaining information from reading, which involves the creation of flashcards out of electronic articles.

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Annotation 7601054420236

Articles in the reading list are prioritized by the user.

status	not read	reprioritisations
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started reading on		finished reading on

Incremental Reading
rticles one at a time, the method works by keeping a large reading list of electronic articles or books (often dozens or hundreds of them) and reading parts of several articles in each session. <span>Articles in the reading list are prioritized by the user. In the course of reading, key points of articles are broken up into flashcards, which are then learned and reviewed over an extended period of time with the help of a spaced repetition

Annotation 7601055993100

In the course of reading, key points of articles are broken up into flashcards, which are then learned and reviewed over an extended period of time with the help of a spaced repetition algorithm.

status	not read	reprioritisations
last reprioritisation on		suggested re-reading day
started reading on		finished reading on

Incremental Reading
reading list of electronic articles or books (often dozens or hundreds of them) and reading parts of several articles in each session. Articles in the reading list are prioritized by the user. <span>In the course of reading, key points of articles are broken up into flashcards, which are then learned and reviewed over an extended period of time with the help of a spaced repetition algorithm. This use of flashcards at later stages of the process is based on the spacing effect (the phenomenon whereby learning is greater when studying is spread out over time) and the testing e

Annotation 7601069886732

PostgreSQL 16.1 Documentation (whole document)

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pdf

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Annotation 7601074343180

Effective Go (whole document)

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Effective Go - The Go Programming Language
> Packages Community navigate_next navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation Effective Go <span>Effective Go Table of Contents Introduction Examples Formatting Commentary Names Package names Getters Interface names MixedCaps Semicolons Control structures If Redeclaration and reassignment For S

Annotation 7601078275340

Go Documentation (whole page)

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Documentation - The Go Programming Language
brary Release Notes <div> Packages Community navigate_next navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> <span>Documentation The Go programming language is an open source project to make programmers more productive. Go is expressive, concise, clean, and efficient. Its concurrency mechanisms make it easy to wr

Annotation 7601083518220

Quick Start - React (whole document)

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Quick Start – React
h Effects You Might Not Need an Effect Lifecycle of Reactive Effects Separating Events from Effects Removing Effect Dependencies Reusing Logic with Custom Hooks Is this page useful? Learn React <span>Quick Start Welcome to the React documentation! This page will give you an introduction to the 80% of React concepts that you will use on a daily basis. You will learn How to create and nest compon

Annotation 7601087712524

React Reference Overview (whole document)

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React Reference Overview – React
e Hatches REACT API Hooks Components APIs Legacy APIs REACT DOM API Components APIs Client APIs Server APIs GET INVOLVED React Community STAY INFORMED React Blog Is this page useful? React Docs <span>React Reference Overview This section provides detailed reference documentation for working with React. For an introduction to React, please visit the Learn section. Our The React reference documentation is bro

Annotation 7601098984716

自动控制的定义

所谓自动控制，是指在没有人直接参与的情况下用外加的设备或装置（控制装置或控制器）使机器、设备或生产过程（统称被控对象）的某个工作状态或参数（被控量）自动地按照预定的规律运行。例如，数控车床按照预定程序自动地切削工件；化学反应炉的温度或压力自动地维持恒定；雷达和计算机组成的导弹发射和制导系统，自动地将导弹引导到敌方目标；无人驾驶飞机按照预定航迹自动升降和飞行；人造卫星准确地进人预定轨道运行并回收等，这一切都是以应用高水平的自动控制技术为前提的。

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Flashcard 7601100819724

Question

所谓自动控制，是指[自动控制定义]。例如，数控车床按照预定程序自动地切削工件；化学反应炉的温度或压力自动地维持恒定；雷达和计算机组成的导弹发射和制导系统，自动地将导弹引导到敌方目标；无人驾驶飞机按照预定航迹自动升降和飞行；人造卫星准确地进人预定轨道运行并回收等，这一切都是以应用高水平的自动控制技术为前提的。

Answer

在没有人直接参与的情况下用外加的设备或装置（控制装置或控制器）使机器、设备或生产过程（统称被控对象）的某个工作状态或参数（被控量）自动地按照预定的规律运行

status	not learned	measured difficulty	37% [default]	last interval [days]
repetition number in this series	0	memorised on		scheduled repetition
scheduled repetition interval		last repetition or drill

自动控制的定义
所谓自动控制，是指在没有人直接参与的情况下用外加的设备或装置（控制装置或控制器）使机器、设备或生产过程（统称被控对象）的某个工作状态或参数（被控量）自动地按照预定的规律运行。例如，数控车床按照预定程序自动地切削工件；化学反应炉的温度或压力自动地维持恒定；雷达和计算机组成的导弹发射和制导系统，自动地将导弹引导到敌方目标；无人驾驶飞机按照预定航迹自动升降和飞行；人造卫星准确地进人预定轨道运行并回收等，这一切都是以应用高水平的自动控制技术为前提的。

Annotation 7601104751884

Go is expressive, concise, clean, and efficient.

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Documentation - The Go Programming Language
Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation The Go programming language is an open source project to make programmers more productive. <span>Go is expressive, concise, clean, and efficient. Its concurrency mechanisms make it easy to write programs that get the most out of multicore and networked machines, while its novel type system enables flexible and modular program con

Annotation 7601106324748

Go's concurrency mechanisms make it easy to write programs that get the most out of multicore and networked machines

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Documentation - The Go Programming Language
og Go project Get connected <div> Documentation The Go programming language is an open source project to make programmers more productive. Go is expressive, concise, clean, and efficient. <span>Its concurrency mechanisms make it easy to write programs that get the most out of multicore and networked machines, while its novel type system enables flexible and modular program construction. Go compiles quickly to machine code yet has the convenience of garbage collection and the power of run-ti

Annotation 7601108684044

Go's novel type system enables flexible and modular program construction.

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Documentation - The Go Programming Language
rogrammers more productive. Go is expressive, concise, clean, and efficient. Its concurrency mechanisms make it easy to write programs that get the most out of multicore and networked machines, <span>while its novel type system enables flexible and modular program construction. Go compiles quickly to machine code yet has the convenience of garbage collection and the power of run-time reflection. It's a fast, statically typed, compiled language that feels like

Annotation 7601111043340

Go compiles quickly to machine code yet has the convenience of garbage collection and the power of run-time reflection.

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last reprioritisation on		suggested re-reading day
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Documentation - The Go Programming Language
s concurrency mechanisms make it easy to write programs that get the most out of multicore and networked machines, while its novel type system enables flexible and modular program construction. <span>Go compiles quickly to machine code yet has the convenience of garbage collection and the power of run-time reflection. It's a fast, statically typed, compiled language that feels like a dynamically typed, interpreted language. Getting Started Installing Go Instructions for downloading and installing Go.

Annotation 7601112616204

Go is a fast, statically typed, compiled language that feels like a dynamically typed, interpreted language.

status	not read	reprioritisations
last reprioritisation on		suggested re-reading day
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Documentation - The Go Programming Language
its novel type system enables flexible and modular program construction. Go compiles quickly to machine code yet has the convenience of garbage collection and the power of run-time reflection. <span>It's a fast, statically typed, compiled language that feels like a dynamically typed, interpreted language. Getting Started Installing Go Instructions for downloading and installing Go. Tutorial: Getting started A brief Hello, World tutorial to get started. Learn a bit about Go code, tools, p

Annotation 7601122839820

Tutorial: Create a Go module (whole document)

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Tutorial: Create a Go module - The Go Programming Language
vigate_next navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation Tutorials Tutorial: Create a Go module <span>Tutorial: Create a Go module Table of Contents Prerequisites Start a module that others can use This is the first part of a tutorial that introduces a few fundamental features of the Go language. If you're just get

Annotation 7601127296268

Tutorial: Get started with Go (whole document)

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Tutorial: Get started with Go - The Go Programming Language
igate_next navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation Tutorials Tutorial: Get started with Go <span>Tutorial: Get started with Go Table of Contents Prerequisites Install Go Write some code Call code in an external package Write more code In this tutorial, you'll get a brief introduction to Go programming. Along th

Annotation 7601131228428

Tutorial: Get started with Go (whole document)

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Annotation 7601136209164

Tutorial: Getting started with multi-module workspaces (whole document)

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Tutorial: Getting started with multi-module workspaces - The Go Programming Language
eCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation Tutorials Tutorial: Getting started with multi-module workspaces <span>Tutorial: Getting started with multi-module workspaces Table of Contents Prerequisites Create a module for your code Create the workspace Download and modify the golang.org/x/example/hello module Learn more about workspaces This tutorial in

Annotation 7601141452044

Tutorial: Developing a RESTful API with Go and Gin (whole document)

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Tutorial: Developing a RESTful API with Go and Gin - The Go Programming Language
eforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation Tutorials Tutorial: Developing a RESTful API with Go and Gin <span>Tutorial: Developing a RESTful API with Go and Gin Table of Contents Prerequisites Design API endpoints Create a folder for your code Create the data Write a handler to return all items Write a handler to add a new item Write a handler

Annotation 7601146170636

Tutorial: Getting started with generics (whole document)

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Tutorial: Getting started with generics - The Go Programming Language
navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation Tutorials Tutorial: Getting started with generics <span>Tutorial: Getting started with generics Table of Contents Prerequisites Create a folder for your code Add non-generic functions Add a generic function to handle multiple types Remove type arguments when calling the generic fu

Annotation 7601150889228

Tutorial: Getting started with fuzzing (whole document)

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Tutorial: Getting started with fuzzing - The Go Programming Language
t navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation Tutorials Tutorial: Getting started with fuzzing <span>Tutorial: Getting started with fuzzing This tutorial introduces the basics of fuzzing in Go. With fuzzing, random data is run against your test in an attempt to find vulnerabilities or crash-causing inputs. Some examples of

Annotation 7601155607820

Writing Web Applications (whole document)

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Writing Web Applications - The Go Programming Language
igate_next navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation /doc/articles/ Writing Web Applications <span>Writing Web Applications Table of Contents Introduction Getting Started Data Structures Introducing the net/http package (an interlude) Using net/http to serve wiki pages Editing Pages The html/template package

Annotation 7601160326412

How to Write Go Code (whole document)

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How to Write Go Code - The Go Programming Language
kages Community navigate_next navigate_beforeCommunity Recorded Talks Meetups open_in_new Conferences open_in_new Go blog Go project Get connected <div> Documentation How to Write Go Code <span>How to Write Go Code Table of Contents Introduction Code organization Your first program Importing packages from your module Importing packages from remote modules Testing What's next Getting help Introduct

Annotation 7601165307148

A Tour of Go (whole document; follow link)

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Documentation - The Go Programming Language
g a simple web application. How to write Go code This doc explains how to develop a simple set of Go packages inside a module, and it shows how to use the go command to build and test packages. <span>A Tour of Go An interactive introduction to Go in four sections. The first section covers basic syntax and data structures; the second discusses methods and interfaces; the third is about Generics;

Edited, memorised or added to reading queue

on 25-Nov-2023 (Sat)

pdf

Roséole syphilitique

Roséole syphilitique

Disparaît en 7 à 10 jours

Absence de signes fonctionnels

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6 semaines

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30 %

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Elles siègent électivement à cheval sur les plis palmaires

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FAUX

La Syphilis secondaire est marquée par plusieurs éruptions cutanéo-muqueuses entrecoupées de phases asymptomatiques de quelques semaines ou mois

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30 % des chancres vont présenter des signes de secondaire

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FAUX

Régression spontanée du chancre sans séquelle en quelques semaines.

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THORACIC aorta

(50% ascending aorta, 20% arch, 30% descending aorta)

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