Edited, memorised or added to reading queue

on 04-Nov-2016 (Fri)

Do you want BuboFlash to help you learning these things? Click here to log in or create user.

Annotation 1414842944780

M2 muscarinic receptors act via a Gi type receptor, which causes a decrease in cAMP in the cell, generally leading to inhibitory-type effects. They appear to serve as autoreceptors.[10]

In addition, they modulate muscarinic potassium channels.[11][12] In the heart, this contributes to a decreased heart rate. They do so by the G beta gamma subunit of the G protein coupled to M2. This part of the G protein can open K+ channels in the parasympathetic notches in the heart, which causes an outward current of potassium, which slows down the heart rate.
statusnot read reprioritisations
last reprioritisation on suggested re-reading day
started reading on finished reading on

Muscarinic acetylcholine receptor M2 - Wikipedia
is claim instead found no significant association between the CHRM2 gene and intelligence. [8] Olfactory behavior[edit] Mediating olfactory guided behaviors (e.g. odor discrimination, aggression, mating) [9] Mechanism of action[edit] <span>M 2 muscarinic receptors act via a G i type receptor, which causes a decrease in cAMP in the cell, generally leading to inhibitory-type effects. They appear to serve as autoreceptors. [10] In addition, they modulate muscarinic potassium channels. [11] [12] In the heart, this contributes to a decreased heart rate. They do so by the G beta gamma subunit of the G protein coupled to M 2 . This part of the G protein can open K + channels in the parasympathetic notches in the heart, which causes an outward current of potassium, which slows down the heart rate. Ligands[edit] Few highly selective M 2 agonists are available at present, although there are several non-selective muscarinic agonists that stimulate M 2 , and a number of selectiv



Annotation 1414846614796

The M2 muscarinic receptors are located in the heart
statusnot read reprioritisations
last reprioritisation on suggested re-reading day
started reading on finished reading on

Muscarinic acetylcholine receptor M2 - Wikipedia
] Contents [hide] 1 Function 1.1 Heart 1.2 IQ 1.3 Olfactory behavior 2 Mechanism of action 3 Ligands 3.1 Agonists 3.2 Antagonists 4 See also 5 References 6 Further reading 7 External links Function[edit] Heart[edit] <span>The M 2 muscarinic receptors are located in the heart, where they act to slow the heart rate down to normal sinus rhythm after positive stimulatory actions of the parasympathetic nervous system, by slowing the speed of depolarization. They